MyBioSource.com's PIP5K1B Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Immunohistochemistry. The PIP5K1B Polyclonal Antibody was generated using PIP5K1B as the antigen and it reacts with Human, Mouse, and Rat.
Description
Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4, 5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III. Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting. The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I å, beta, and ©, which are characterized by phosphorylating PI4P on the 5-hydroxyl. PIPK I å (designated PIPK I beta in mouse) is expressed in brain tissue. PIPK I beta, designated PIPK I a in mouse, is also called STM7. PIPK I © has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys